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Updated: Jul 10, 2026

Targeting Cysteine Thiols for in Vitro Site-specific Glycosylation of Recombinant Proteins
11:25

Targeting Cysteine Thiols for in Vitro Site-specific Glycosylation of Recombinant Proteins

Published on: October 4, 2017

バクテリアのオリゴサカリルトランスフェラーゼによる折りたたまれたタンパク質のN結合型グリコシル化

Michael Kowarik1, Shin Numao, Mario F Feldman

  • 1Institute of Microbiology, Department of Biology, Eidgenössische Technische Hochschule (ETH) Zurich, 8093 Zurich, Switzerland.

Science (New York, N.Y.)
|November 18, 2006
PubMed
まとめ

バクテリアのN結合タンパク質グリコシレーションは,タンパク質転位とは独立して発生します. ユカリオットとは異なり,バクテリアのシステムは,折りたたまれたタンパク質を効率的にグリコシル化し,この重要なタンパク質改変のための明確な進化の経路を示唆しています.

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