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Updated: Jun 23, 2026

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スタチンはAMP活性化タンパク質キナーゼをインビトロおよびインビボで活性化します

Wei Sun1, Tzong-Shyuan Lee, Minjia Zhu

  • 1Division of Biomedical Sciences, University of California, Riverside, Riverside, CA 92521-0121, USA.

Circulation
|November 23, 2006
PubMed
まとめ

スタチンはAMP活性化タンパク質キナーゼ (AMPK) を活性化させ,内皮酸化窒素合成酵素 (eNOS) の活性性を高めます. このAMPK活性化が,酸化窒素の産生と血管新生を促進することによって,スタチンの心血管上の利点を説明しています.

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