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Updated: Jul 8, 2026

Techniques to Induce and Quantify Cellular Senescence
06:51

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腫瘍遺伝子の誘発による衰老は,DNA損傷のチェックポイントによって課される腫瘍形成の障壁の一部です

Jirina Bartkova1, Nousin Rezaei, Michalis Liontos

  • 1Institute of Cancer Biology and Centre for Genotoxic Stress Research, Danish Cancer Society, DK-2100 Copenhagen, Denmark. jb@cancer.dk

Nature
|December 1, 2006
PubMed
まとめ

腫瘍生成の障壁は,腫瘍遺伝子誘発の衰老を含むが,DNA複製ストレスと関連している. このストレスは,DNAの損傷と二重鎖の断裂を含み,がんの進行に対する障壁として作用します.

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