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Updated: Jul 18, 2026

Engineering Cell-permeable Protein
21:08

Engineering Cell-permeable Protein

Published on: December 28, 2009

CHO細胞のリン酸化調節されたCl-チャネルは,システィックフィブロシス遺伝子を安定的に発現させる

J A Tabcharani1, X B Chang, J R Riordan

  • 1Department of Physiology, McGill University, Montreal, Québec, Canada.

Nature
|August 15, 1991
PubMed
まとめ

性線維症遺伝子は,非上皮細胞の塩化チャネルを発現し,循環型AMPによって活性化され,リン酸化によって調節されます. この研究は,システィックフィブロシスのトランスメブランレギュレータチャネルの直接のリン酸化制御を実証しています.

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