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Updated: Jul 10, 2026

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability
09:27

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability

Published on: April 22, 2016

ステレオ化学的に互いを補完するバイオカタリストのペアの作成

Gavin J Williams1, Thomas Woodhall, Lorna M Farnsworth

  • 1Astbury Centre for Structural Molecular Biology and School of Chemistry, University of Leeds, Leeds, LS2 9JT, United Kingdom.

Journal of the American Chemical Society
|December 15, 2006
PubMed
まとめ

研究者は,カーボン-カーボン結合形成における顔面の選択性の低下を克服するために,指向進化を用いて,N-アセチルニューアミン酸リアゼ (N-Acetylneuraminic acid lyase,NAL) 変種を設計した. これらの補完的な生物触媒は,シアル酸模倣剤の高度なダイアステロセレクティブ合成を可能にし,合成化学の応用を拡大します.

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Induced-fit Model

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Enzymes

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Catalysis

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Heterogeneous Catalysis

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