関連する実験動画

Updated: Jul 10, 2026

A High-throughput-compatible FRET-based Platform for Identification and Characterization of Botulinum Neurotoxin Light Chain Modulators
10:30

A High-throughput-compatible FRET-based Platform for Identification and Characterization of Botulinum Neurotoxin Light Chain Modulators

Published on: December 27, 2013

ボトリヌム神経毒Bは,高親和性と特異性を持つタンパク質受容体を認識します

Rongsheng Jin1, Andreas Rummel, Thomas Binz

  • 1Howard Hughes Medical Institute, Stanford University, Stanford, California 94305, USA.

Nature
|December 15, 2006
PubMed
まとめ

ボトリヌム神経毒素 (BoNTs) は,シナプトタグミンIIとギャングリオシド経由で細胞と結合する. BoNT/B結合に関するこの構造的洞察は,この神経毒素に対するワクチンや阻害剤の開発を進めます.

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