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フィブリロゲネシス前の集積ペプチドのエンカプスレーションとNMR

Kristi L Lazar1, Josh W Kurutz, Robert Tycko

  • 1Department of Chemistry, The University of Chicago, Chicago, IL 60637, USA.

Journal of the American Chemical Society
|December 21, 2006
PubMed
まとめ

研究者らは,ペプチドを膀内に封じ込み,集積を防止し,溶解性オリゴマーの構造分析を可能にする方法を開発しました. このテクニックは,以前にアクセス不可能な細胞毒性の種を研究することによって,アルツハイマー病のようなアミロイド疾患の洞察を提供します.

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