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分子シミュレーションによって評価された視界における網膜のカウンターオンスイッチ機構

Karina Martínez-Mayorga1, Michael C Pitman, Alan Grossfield

  • 1Departments of Chemistry and Physics, University of Arizona, Tucson, AZ 85721, USA.

Journal of the American Chemical Society
|December 21, 2006
PubMed
まとめ

ロドプシン活性化には,対対離子スイッチメカニズムが含まれています. 分子ダイナミクスシミュレーションとNMRスペクトルは,Glu113とGlu181の両方がメタI状態の網膜のプロトン化シフ基を安定させることを示しています.

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