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Updated: May 12, 2026

Purification of the Cystic Fibrosis Transmembrane Conductance Regulator Protein Expressed in Saccharomyces cerevisiae
15:12

Purification of the Cystic Fibrosis Transmembrane Conductance Regulator Protein Expressed in Saccharomyces cerevisiae

Published on: May 10, 2014

核酸トリホスファートは,CFTR塩化物チャネルを開くために必要です

M P Anderson1, H A Berger, D P Rich

  • 1Howard Hughes Medical Institute, Department of Internal Medicine, University of Iowa College of Medicine, Iowa City 52242.

Cell
|November 15, 1991
PubMed
まとめ

サイトソリックATPは,リン酸化CFTRチャネルを開くために不可欠であり,核酸結合ドメイン1 (NBD1) による水解が活性化に潜在的に十分である. これは,CFTR変異がクロライドチャネル機能をどのように破壊するかを説明します.

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