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Updated: Jul 8, 2026

Visualizing Leukocyte Rolling and Adhesion in Angiotensin II-Infused Mice: Techniques and Pitfalls
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Visualizing Leukocyte Rolling and Adhesion in Angiotensin II-Infused Mice: Techniques and Pitfalls

Published on: January 4, 2018

腫瘍死滅因子-αは,Lepr(db) マウスの内皮機能不全を誘発する.

Xue Gao1, Souad Belmadani, Andrea Picchi

  • 1Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, TX, USA.

Circulation
|January 4, 2007
PubMed
まとめ

腫瘍死滅因子アルファ (TNF) は,酸化ストレスを増加させることで,2型糖尿病における内皮機能不全を誘発する. TNFまたはその下流効果をブロックすると,糖尿病のマウスの血管機能が回復します.

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Lethal Alleles02:41

Lethal Alleles

Agouti: A Lethal Allele
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...