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一般人口の先天性心疾患:流行率と年齢分布の変化
Ariane J Marelli1, Andrew S Mackie, Raluca Ionescu-Ittu
1McGill Adult Unit for Congenital Heart Disease, McGill University Health Center, 1650 Cedar Ave, Montreal, Quebec, Canada H3G 1A4. ariane.marelli@mcgill.ca
Circulation
|January 11, 2007
まとめ
生まれながらの心疾患 (CHD) の罹患率は1985年から2000年まで増加し,成人では著しく増加しました. 2000年までに,成人と子供は重度のCHD症例のほぼ同じ割合を占めていた.
科学分野:
- 心臓病学 心臓病学
- 小児科は小児科です.
- 公衆衛生は公衆衛生である.
背景:
- 生まれながらの心疾患 (CHD) の流行病学的変化に関する経験的データは限られている.
- CHDの罹患率と年齢分布の動向を理解することは,医療計画において極めて重要です.
研究 の 目的:
- 発症率,年齢分布,および重症性および他の形態のCHDの成人と子供の比率を決定する.
- 1985年から2000年までのCHD流行病学の動向を分析する.
主な方法:
- ケベック州の体系的な診断と請求記録を備えた行政データベースを利用した.
- 特定の診断コード (例えば,フォロトの四行,トランクス・アテリオサス) を使用して,重度のCHDを定義します.
- 1985年,1990年,1995年,2000年の重症性およびその他のCHDの計算された罹患率.
主要な成果:
- 2000年,全CHDの罹患率は成人1000人当たり4.09,重度のCHDは1000人当たり0.38 (9%) でした.
- 重度の心血管疾患の患者の平均年齢は,1985年の11歳から2000年の17歳に増加した (P<0,0001).
- 重度の心血管疾患の罹患率は,1985年から2000年の間に子供と比較して成人の間で著しく増加し,2000年には重度の心血管疾患症例の49%を成人が占めた.
結論:
- 大人の罹患率と重度の心血管疾患の患者の平均年齢の両方が増加しています.
- 2000年までに,重度の心臓病を患っている成人と子供の数はほぼ同じだった.
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