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Updated: Jul 17, 2026

In Vitro Bioluminescence Assay to Characterize Circadian Rhythm in Mammary Epithelial Cells
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人間の昼夜変異のモデリングは,PER2によるクロック調節に関する洞察をもたらします

Y Xu1, K L Toh, C R Jones

  • 1Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA.

Cell
|January 16, 2007
PubMed
まとめ

ヒトの2期 (hPER2) 遺伝子変異は,PER2のリン酸化に影響することで,高度睡眠相症候群を引き起こす. この変異を持つトランス遺伝子マウスは,人間の状態を模倣し,カゼインキナーゼIデルタによる昼夜時計の調節に関する洞察を明らかにします.

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