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Updated: Jul 17, 2026

Synthesis, Hemoglobin Encapsulation and Biorthogonal PEGylation in Hierarchically Porous UiO-66 Nanoparticles for Oxygen Delivery Applications
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Synthesis, Hemoglobin Encapsulation and Biorthogonal PEGylation in Hierarchically Porous UiO-66 Nanoparticles for Oxygen Delivery Applications

Published on: May 8, 2026

グリコフォリンAのヘム結合部位を工学的に設計することによって,機能的な膜タンパク質の設計

Jeanine M Cordova1, Pamela L Noack, Simon A Hilcove

  • 1Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona 85287-1604, USA.

Journal of the American Chemical Society
|January 18, 2007
PubMed
まとめ

研究者は,ヘム結合部位をグリコホルリンAに組み込むことにより,機能モデル膜タンパク質ME1を設計した. この新しいタンパク質はヘムを結合し,その構造を維持し,酸化反応を触媒化し,タンパク質-コファクター相互作用の洞察を提供します.

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