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Updated: Jul 9, 2026

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TGF-βとRas/MAPKの信号伝達の統合は,p53のリン酸化によって行われる

Michelangelo Cordenonsi1, Marco Montagner, Maddalena Adorno

  • 1Department of Medical Biotechnologies, Section of Histology and Embryology, University of Padua, Padua, Italy.

Science (New York, N.Y.)
|January 20, 2007
PubMed
まとめ

細胞シグナリングは,成長因子β (TGF-β) と受容体チロシンキナーゼ (RTK) 経路の変換を統合する. RTK/Ras/MAPKの活動はp53とリンクし,細胞運命を制御するTGF-βシグナリングを可能にします.

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