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An Improved Method for Collection of Cerebrospinal Fluid from Anesthetized Mice
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Foxp3の占有と,T細胞刺激中に重要な標的遺伝子の調節

Alexander Marson1, Karsten Kretschmer, Garrett M Frampton

  • 1Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.

Nature
|January 24, 2007
PubMed
まとめ

フォークヘッドボックスP3 (Foxp3) は,T細胞機能に重要な遺伝子を直接調節する. Foxp3は,主として,自己免疫を予防し,T細胞の制御機能を維持するために不可欠な標的遺伝子の活性化を抑制します.

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