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運動テストの開始時の心拍数上昇の予知値

Nicholas J Leeper¹, Frederick E Dewey, Euan A Ashley

¹Stanford University Medical Center, Stanford University Medical School, Calif, USA. nleeper@cvmed.stanford.edu

|January 24, 2007

まとめ

運動中に心拍数が急速に上昇することは,よりよい生存率を予測します. しかし,ピーク運動の心拍数とデューク・トレッドミルのスコアは,トレッドミルのテストを受ける患者の心血管の予後を予測するより強力な指標です.

科学分野:

心臓病学心臓病学
運動生理学運動生理学
予測バイオマーカー

背景:

ダイナミックな運動に対する初期心拍数応答の予後値については,現在調査中です.
以前の研究では,トレッドミルのテスト以外の運動方法を使用しました.

研究の目的:

臨床トレッドミール試験中の早期心拍数パラメータの予後的意義を評価する.
初期心拍数変化が死亡リスクを予測するかどうかを判断する.

主な方法:

クリニカル・トレッドミルのテストを受けた1959人の患者を分析した.
多変量コックス生存分析は,アウトカムを評価するために使用されました.
追跡期間は平均で5.4年,全因 197例,心血管疾患による死亡 74例でした.

主要な成果:

初期ワークロードで心拍数上昇の低下は,全原因死亡率の増加と相関しています.
運動能力の3分の1で心拍数上昇は,全原因および心血管リスクの両方を予測しました.
ピーク運動の心拍数上昇は,心血管疾患の予後における最も強い心拍数予測因子でした.

結論:

初期の心拍数急激な上昇は,生存率の向上と関連しています.
ピークエクササイズ心拍数とデューク・トレッドミルのスコアは,初期の心拍数パラメータと比較して,心臓血管の予後を予測する優れた指標です.

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