6-メルカプトプーリンによって核受容体Nur77の活性化により,ネオインティマ形成から保護されます

Nuno M M Pires1, Thijs W H Pols, Margreet R de Vries

  • 1Gaubius Laboratory, TNO-Quality of Life, Leiden, The Netherlands.

Circulation
|January 24, 2007
PubMed
まとめ

6-メルカプトプーリン (6-MP) は,核受容体Nur77.7を活性化することによって,血管の滑らかな筋肉細胞の増殖と復元を阻害する. この活性化は,DNA合成とネオインティマの形成を減少させ,インステント回復症に対する潜在的な治療法を提供します.

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