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Updated: Jul 10, 2026

Prediction and Validation of Gene Regulatory Elements Activated During Retinoic Acid Induced Embryonic Stem Cell Differentiation
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Runx2によるrRNA遺伝子のミトス占有および系統特有の転写制御

Daniel W Young1, Mohammad Q Hassan, Jitesh Pratap

  • 1Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.

Nature
|January 26, 2007
PubMed
まとめ

哺乳類のRunx2は,RNAポリメラーゼI (Pol I) によってリボソームRNA (rRNA) の合成を抑制し,細胞の運命を細胞の成長と結びつける. Runx2欠乏症は,rRNAの転写とタンパク質の合成を促進する.

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