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Updated: May 8, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
10:27

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells

Published on: March 9, 2012

PRAKは,RAS誘発の衰老と腫瘍抑制に不可欠です

Peiqing Sun1, Naoto Yoshizuka, Liguo New

  • 1Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA. pqsun@scripps.edu

Cell
|January 27, 2007
PubMed
まとめ

腫瘍抑制剤である腫瘍遺伝子誘発性衰老は,p38調節/活性化タンパク質キナーゼ (PRAK) によって媒介されます. 腫瘍性ラスの反応としてp38によるPRAKの活性化は老化を促進し,腫瘍の発達を抑制する.

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Identification of EGFR and RAS Inhibitors using Caenorhabditis elegans08:12

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