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FoxOsは,系統限定の冗長性腫瘍抑制剤であり,内皮細胞ホメオスタシスを調節する

Ji-Hye Paik1, Ramya Kollipara, Gerald Chu

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA 02115, USA.

Cell
|January 27, 2007
PubMed
まとめ

哺乳類のフォークヘッドボックスO (FoxO) 転写因子は,重要な腫瘍抑制剤である. すべてのFoxOを削除すると,がんが促進され,腫瘍的状態を予防し,血管ホメオスタシスを維持する役割が強調されます.

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