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Updated: Jul 15, 2026

Homogeneous Glycoconjugate Produced by Combined Unnatural Amino Acid Incorporation and Click-Chemistry for Vaccine Purposes
13:53

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膀性口腔炎ウイルスグリコプロテインGのプレフュージョン形態の構造

Stéphane Roche1, Félix A Rey, Yves Gaudin

  • 1CNRS, Unité Mixte de Recherche (UMR) 2472, Institut National de la Recherche Agronomique (INRA), UMR 1157, Institut Fédératif de Recherche 115, Laboratoire de Virologie Moléculaire et Structurale, 91198, Gif sur Yvette, France.

Science (New York, N.Y.)
|February 10, 2007
PubMed
まとめ

膀性口腔炎ウイルスのグリコプロテインG (G) は,低pHで誘発された構造変化を経て膜を融合させます. そのプレフュージョン構造は三脚の形を明らかにし,ウイルス膜の相互作用のための融合ループを暴露し,膜の融合を誘発します.

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