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Updated: Jul 16, 2026

Assays for Validating Histone Acetyltransferase Inhibitors
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Assays for Validating Histone Acetyltransferase Inhibitors

Published on: August 6, 2020

アズマミドとヒストン脱エチラゼの抑制活性に関する分子洞察

Nakia Maulucci1, Maria Giovanna Chini, Simone Di Micco

  • 1Department of Chemistry, University of Salerno, Via Ponte Don Melillo, 84084 Fisciano, Salerno, Italy.

Journal of the American Chemical Society
|February 22, 2007
PubMed
まとめ

強力なヒストン脱酸化酵素 (HDAC) 阻害剤であるアズマミドEは,その活性と結合を理解するために,合成変種を介して研究されました. この研究は,がん治療のための新しいHDAC阻害剤の設計に役立ちます.

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