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Updated: Jul 6, 2026

Genome-wide Analysis using ChIP to Identify Isoform-specific Gene Targets
11:19

Genome-wide Analysis using ChIP to Identify Isoform-specific Gene Targets

Published on: July 7, 2010

レチノブラストーマ結合タンパク質RBP2は,H3K4デメチラゼである

Robert J Klose1, Qin Yan, Zuzana Tothova

  • 1Howard Hughes Medical Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Cell
|February 27, 2007
PubMed
まとめ

レチノブラストーマ結合タンパク質2 (RBP2) は,活性遺伝子のマーカーであるトリメチルヒストンH3ライシン4 (H3K4me3) を消去します. RBP2欠乏症はサイトカインの遺伝子転写を強化し,表遺伝的調節におけるその役割を明らかにします.

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