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Updated: Mar 30, 2026

Single Nucleotide Polymorphism-sensitive FISH Detection of Locus-specific Ribosomal RNA Transcription in Drosophila melanogaster
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非コーディングRNAと,モノアレル基因発現における核内定位

Pok Kwan Yang1, Mitzi I Kuroda

  • 1Howard Hughes Medical Institute, Boston, Massachusetts 02115, USA.

Cell
|February 27, 2007
PubMed
まとめ

モノアレル基因発現は,核内のノンコーディング転写とアレル分離に依存する. 微分染色体マークを含むこれらのメカニズムは,遺伝子調節を理解するための鍵です.

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In eukaryotes, transcription and translation are compartmentalized; an mRNA is first synthesized in the nucleus and then selectively transported to the cytoplasm for protein synthesis. Before transport, a pre-mRNA undergoes several steps of post-transcriptional modifications including splicing, 5' capping, and the addition of a poly-adenine tail. Various proteins bind to the pre-mRNA during these modifications. The mRNA transport takes place with the help of multiple proteins playing...
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