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Updated: May 7, 2026

A High-throughput Calcium-flux Assay to Study NMDA-receptors with Sensitivity to Glycine/D-serine and Glutamate
04:48

A High-throughput Calcium-flux Assay to Study NMDA-receptors with Sensitivity to Glycine/D-serine and Glutamate

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CNGA2チャネルにおける活性化ゲートにリガンド結合を関連付ける

Christoph Biskup1, Jana Kusch, Eckhard Schulz

  • 1Institut für Physiologie II, Friedrich-Schiller-Universität Jena, D 07740 Jena, Germany.

Nature
|February 27, 2007
PubMed
まとめ

研究者らは,サイクルヌクレオチドゲート (CNG) イオンチャネル活性化を調査した. 彼らは,第2リガンド結合ステップがチャネル開通に不可欠であり,感覚伝導におけるサブユニット相互作用を明らかにすることを発見しました.

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