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皮質細胞内在のIKK-β発現は腸内免疫ホメオスタシスを調節する

Colby Zaph1, Amy E Troy, Betsy C Taylor

  • 1Department of Pathobiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

Nature
|February 27, 2007
PubMed
まとめ

腸内皮質細胞 (IECs) は免疫反応を調節する. IECに特異的なIKK-βの欠損はTヘルパー2細胞の免疫を低下させ,寄生虫感染中に重度の腸炎を引き起こします.

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