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Updated: Jul 13, 2026

Preparation of Fungal and Plant Materials for Structural Elucidation Using Dynamic Nuclear Polarization Solid-State NMR
09:37

Preparation of Fungal and Plant Materials for Structural Elucidation Using Dynamic Nuclear Polarization Solid-State NMR

Published on: February 12, 2019

バクテリアの細胞壁バイオシンセシスのトランスグリコシル化段階の構造的洞察

Andrew L Lovering1, Liza H de Castro, Daniel Lim

  • 1Department of Biochemistry and Molecular Biology, and Center for Blood Research, University of British Columbia, 2350 Health Sciences Mall, Vancouver, Canada.

Science (New York, N.Y.)
|March 10, 2007
PubMed
まとめ

ペプチドグリカングリコシルトランスフェラーゼ (GT) は,細菌の細胞壁に不可欠であり,重要な抗生物質標的である. 構造分析により,それらのユニークな折りたたみと触媒メカニズムが明らかになり,耐性細菌に対する薬物開発の新たな道が開かれている.

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