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Updated: Jul 16, 2026

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
12:24

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers

Published on: July 17, 2012

標的型腫瘍イメージングのための酵素活性化光センサー.

Mako Kamiya1, Hisataka Kobayashi, Yukihiro Hama

  • 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Journal of the American Chemical Society
|March 14, 2007
PubMed
まとめ

新しい光探知機であるAM-TG-betaGalは,ベータ-ガラクトシダースの活性に対する敏感な in vivo 光学画像を可能にします. このレポーター酵素イメージング戦略は,マウスの小さな腫瘍を視覚化することに成功し,腹腔鏡手術などの臨床応用の可能性を提供しています.

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...