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Updated: Jun 26, 2026

In Vivo Nanovector Delivery of a Heart-specific MicroRNA-sponge
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ストレスに依存する心臓の成長と遺伝子発現をマイクロRNAによって制御する

Eva van Rooij1, Lillian B Sutherland, Xiaoxia Qi

  • 1Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.

Science (New York, N.Y.)
|March 24, 2007
PubMed
まとめ

アルファ-ミオシン重鎖 (alphaMHC) 遺伝子によってコード化された心臓特有のマイクロRNA (miR-208) は,ストレスに対する反応として心臓の成長と機能の変化に不可欠です. このマイクロRNAは重要なタンパク質を調節し,心臓の収縮性と構造に影響を与えます.

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