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Updated: May 10, 2026

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

大規模な複製研究における急性冠動脈症候群の報告された遺伝的リスク因子の非検証

Thomas M Morgan1, Harlan M Krumholz, Richard P Lifton

  • 1Department of Genetics, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Conn 06510, USA. morgan_t@kids.wustl.edu

JAMA
|April 12, 2007
PubMed
まとめ

この研究では,検査された85種類の遺伝子変異が,急性冠動脈症候群 (ACS) の危険因子であるという証拠は見つかりませんでした. 遺伝的危険因子を臨床実務で使用する前に,堅牢な複製が必要である.

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