食事の摂取のホルモンによるコントロール
Anthony P Coll1, I Sadaf Farooqi, Stephen O'Rahilly
1Department of Clinical Biochemistry, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Cambridge CB2 2XY, United Kingdom.
Cell
|April 24, 2007
まとめ
ペプチドやステロイドのような体内のホルモンは,脳の重要な領域に作用することによって食欲を調節します. このレビューは,脂肪細胞,腸,および臓からのこれらのホルモンが食物摂取にどのように影響するかの証拠を合成しています.
科学分野:
- エンドクリノロジー エンドクリノロジー
- 神経科学は神経科学である.
- メタボリズムは
背景:
- 食欲の調節は,多数の内生シグナル伝達分子によって影響される複雑なプロセスです.
- ホルモンは,エネルギーバランスと食物の摂取を媒介する上で重要な役割を果たします.
- 主な調節部位には,下垂体,脳幹,および自律神経系が含まれています.
研究 の 目的:
- 食欲制御における循環ホルモンの役割に関する最近の科学的証拠を合成する.
- 脂肪細胞,消化器系,および臓から発生するホルモンの概要.
- これらのホルモンが食物摂取に影響を与えるメカニズムを解明する.
主な方法:
- 最近の科学出版物の文献レビュー.
- 実験的および観察的研究からの証拠の合成.
- 食欲調節に関与するホルモン経路の分析.
主要な成果:
- 循環するペプチドとステロイドは食欲の重要な調節因子である.
- 脂肪組織,消化管,および臓からのホルモンは,食物の摂取に大きく影響します.
- これらのホルモンは,脳と自律神経系の神経経路を通じて効果を発揮します.
結論:
- ホルモンシグナル伝達は,食欲の生理学的コントロールの中心にある.
- これらのホルモンの作用を理解することは,代謝障害に対処するために非常に重要です.
- これらの経路に関するさらなる研究は,食欲管理のための治療的標的を明らかにする可能性があります.
関連する概念動画
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