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Updated: Jul 13, 2026

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
10:17

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations

Published on: November 3, 2010

フィンランドの2型糖尿病に関する全ゲノム関連研究により,複数の感受性変異が検出されました

Laura J Scott1, Karen L Mohlke, Lori L Bonnycastle

  • 1Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA.

Science (New York, N.Y.)
|April 28, 2007
PubMed
まとめ

研究者らは,フィンランド人集団における2型糖尿病 (T2D) リスクに関連した新しい遺伝子変異を特定した. この研究は,T2Dの既知の遺伝的景観を拡張し,合計で確認されたロシを少なくとも10に持ち込みます.

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Generation of High Quality Chromatin Immunoprecipitation DNA Template for High-throughput Sequencing (ChIP-seq)

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Comparing Copy Number Variations and SNPs

Sequencing of the human genome has opened up several best-kept secrets of the genome. Scientists have identified thousands of genome variations that exist within a population. These variations can be a single nucleotide or a larger chromosomal variation.
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...
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Genes exist in different versions called alleles, which...