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Updated: Jun 10, 2026

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay (EMSA) and DNA-affinity Precipitation Assay (DAPA)
11:35

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay (EMSA) and DNA-affinity Precipitation Assay (DAPA)

Published on: August 21, 2016

染色体9p21の一般的な変異は,心筋梗塞のリスクに影響します

Anna Helgadottir1, Gudmar Thorleifsson, Andrei Manolescu

  • 1deCODE genetics, Sturlugata 8, IS-101 Reykjavik, Iceland.

Science (New York, N.Y.)
|May 5, 2007
PubMed
まとめ

染色体9p21の近くの一般的な遺伝子変異は,心筋梗塞 (MI) のリスクを大幅に増加させます. この変種を有する個人は,心筋梗塞のリスクが1.64倍,早期発症のリスクが2.02倍高い.

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Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model

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