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ビタミンと老化:NAD+合成への経路

John M Denu1

  • 1Department of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin, 1300 University Avenue, Madison, WI 53706, USA. jmdenu@wisc.edu <jmdenu@wisc.edu>

Cell
|May 8, 2007
PubMed
まとめ

新種のNAD+前駆体であるニコチナミドリボシドは,Sir2デセチラゼの活性を調節することにより,酵母の寿命を延ばします. この寿命延長効果は,カロリー制限とは無関係であり,老化に関する研究に新たな洞察を提供している.

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