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Updated: Jul 15, 2026

Modeling Ligands into Maps Derived from Electron Cryomicroscopy
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Modeling Ligands into Maps Derived from Electron Cryomicroscopy

Published on: July 19, 2024

Mycobacterium tuberculosisからの切断されたヘモグロビン-Nのゲート開く分子スイッチによるリガンド移動のダイナミックな調節

Axel Bidon-Chanal1, Marcelo A Martí, Darío A Estrin

  • 1Departament de Fisicoquímica, Facultat de Farmàcia, Universitat de Barcelona, Avenida Diagonal 643, 08028, Barcelona, Spain.

Journal of the American Chemical Society
|May 10, 2007
PubMed
まとめ

マイコバクテリウム結核は,有害な酸化窒素 (NO) を中和するために,切断されたヘモグロビン-N を使用します. 分子ダイナミクスでは,TyrB10-GlnE11スイッチが,細菌の生存に不可欠なヘム腔にNOの侵入を制御していることが明らかになった.

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