関連する実験動画

Updated: Jul 13, 2026

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
10:17

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations

Published on: November 3, 2010

ヒトのガンマグルタミルカルボキシラーゼのcDNAのクローン化と発現

S M Wu1, W F Cheung, D Frazier

  • 1Department of Biology, University of North Carolina, Chapel Hill 27599-3280.

Science (New York, N.Y.)
|December 13, 1991
PubMed
まとめ

研究者らは,ヒトのガンマ・グルタミル・カルボキシラーゼの遺伝子をクローン化し,ビタミンK依存タンパク質活性に不可欠な酵素である. このクローニングにより,実験室で培った細胞の酵素活性が増加し,血液凝固と骨の代謝に関する研究が進められました.

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What is Gene Expression?01:42

What is Gene Expression?

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Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
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Cell Specific Gene Expression

Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...