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Updated: May 10, 2026

Analysis of Translation Initiation During Stress Conditions by Polysome Profiling
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Analysis of Translation Initiation During Stress Conditions by Polysome Profiling

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ドロソフィラ miR2は偽ポリソームを誘発し,翻訳開始を阻害する

Rolf Thermann1, Matthias W Hentze

  • 1European Molecular Biology Laboratory, Meyerhofstrasse 1, D-69117 Heidelberg, Germany.

Nature
|May 18, 2007
PubMed
まとめ

マイクロRNA (miRs) は,翻訳開始を阻害することによって,タンパク質合成を阻害する. この研究は,miRsがリボソーム組立とは独立して,密度の高い擬多体を形成することを明らかにし,mRNAキャップ構造の重要性を強調しています.

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Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs

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