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関連する概念動画

Epigenetic Regulation01:46

Epigenetic Regulation

Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
Histone Modification02:32

Histone Modification

The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
Acetylation
The enzyme histone acetyltransferase adds acetyl group to the histones. Another enzyme, histone deacetylase,...
Inheritance of Chromatin Structures03:17

Inheritance of Chromatin Structures

Epigenetics is the study of inherited changes in a cell's phenotype without changing the DNA sequences. It provides a form of memory for the differential gene expression pattern to maintain cell lineage, position-effect variegation, dosage compensation, and maintenance of chromatin structures such as telomeres and centromeres. For example, the structure and location of the centromere on chromosomes are epigenetically inherited. Its functionality is not dictated or ensured by the underlying DNA...
Epigenetic Regulation01:46

Epigenetic Regulation

Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
Epigenetic Regulation01:37

Epigenetic Regulation

Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
Gene-Environment Interactions01:20

Gene-Environment Interactions

Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...

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関連する実験動画

Updated: May 7, 2026

Methylated DNA Immunoprecipitation
21:24

Methylated DNA Immunoprecipitation

Published on: January 2, 2009

エピジェネティクスの認識

Adrian Bird1

  • 1Wellcome Trust Centre for Cell Biology, Edinburgh University, The King's Buildings, Edinburgh EH9 3JR, UK.

Nature
|May 25, 2007
PubMed
まとめ

エピジェネティクスは,DNA配列を変えることなく,遺伝子機能がどのように変化するのかを研究しています. このエキサイティングな分野は,遺伝的決定論を超えた生物学への新しい洞察を提供します.

科学分野:

  • 生物学 生物学 生物学とは
  • 遺伝学 遺伝学とは
  • エピジェネティクス エピジェネティクス

背景:

  • 遺伝子の研究は確立されていますが",エピジェネス"という概念は依然として難解です.
  • エピジェネティクスは,過去一年で2,500以上の記事と専用の科学会議で,重要な注目を集めている.
  • それは革命的な科学として提示され,遺伝的決定論の概念に挑戦しています.

研究 の 目的:

  • エピジェネティクスの新興分野を定義し,説明する.
  • 現代の生物学におけるエピジェネティック研究の範囲と重要性を明確にする.

主な方法:

  • この概要は,特定の方法の詳細を記載していません.
  • この分野は,遺伝子調節を研究するために様々な分子生物学技術に依存しています.

主要な成果:

  • 概要は,エピジェネティクスの急速な成長と大衆の関心を強調しています.
  • それは,純粋に遺伝的説明の代替案を提供するダイナミックなフィールドとしての表遺伝学を強調します.

結論:

  • エピジェネティクスは,生物学研究の重要で急速に進化する領域を表しています.

さらに関連する動画

Pattern-based Search of Epigenomic Data Using GeNemo
06:38

Pattern-based Search of Epigenomic Data Using GeNemo

Published on: October 8, 2017

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues
10:41

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues

Published on: April 5, 2018

関連する実験動画

Last Updated: May 7, 2026

Methylated DNA Immunoprecipitation
21:24

Methylated DNA Immunoprecipitation

Published on: January 2, 2009

Pattern-based Search of Epigenomic Data Using GeNemo
06:38

Pattern-based Search of Epigenomic Data Using GeNemo

Published on: October 8, 2017

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues
10:41

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues

Published on: April 5, 2018

  • DNA配列を超えた生物学的複雑性を理解するための枠組みを提供します.