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Updated: Jan 16, 2026

Author Spotlight: Enhancing Coronary Artery Revascularization
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人間のAgo2内のmRNA m7Gキャップ結合型のモチーフは,翻訳を抑制する

Marianthi Kiriakidou1, Grace S Tan, Styliani Lamprinaki

  • 1Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. kiriakim@uphs.upenn.edu

Cell
|May 26, 2007
PubMed
まとめ

人間のアルゴナウト (Ago) タンパク質は,遺伝子発現を調節するためにマイクロRNA (miRNA) に結合します. 研究者らは,m(7) Gキャップに結合するAgoタンパク質のモチーフを発見し,eIF4E募集を阻害することによって翻訳開始を抑制しました.

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