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Updated: Jul 6, 2026

Using Zebrafish Models of Human Influenza A Virus Infections to Screen Antiviral Drugs and Characterize Host Immune Cell Responses
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Using Zebrafish Models of Human Influenza A Virus Infections to Screen Antiviral Drugs and Characterize Host Immune Cell Responses

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鳥インフルエンザN1における驚くべきループの柔軟性と,抗ウイルス薬の設計におけるその影響

Rommie E Amaro1, David D L Minh, Lily S Cheng

  • 1Department of Chemistry & Biochemistry, NSF Center for Theoretical Biological Physics, University of California San Diego, La Jolla, California 92093-0365, USA. ramaro@mccammon.ucsd.edu

Journal of the American Chemical Society
|June 2, 2007
PubMed
まとめ

No abstract available in PubMed .

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Inhibitors Of Virion Release01:25

Inhibitors Of Virion Release

Viral replication and dissemination rely on efficient mechanisms for host cell entry, genome replication, assembly, and release. Influenza viruses, such as types A and B, are negative-sense single-stranded RNA viruses with a segmented genome, that depend on two critical surface glycoproteins to carry out these processes: hemagglutinin (HA) and neuraminidase (NA). HA initiates infection by binding to sialic acid residues on the surface of host epithelial cells, facilitating receptor-mediated...