オリエンテッドな細胞分裂と筋肉の衛星細胞の異質性
Giulio Cossu1, Shahragim Tajbakhsh
1Stem Cell Research Institute, Dibit, San Raffaele, Via Olgettina 58, 20132 Milan, Italy. cossu.giulio@hsr.it
Cell
|June 2, 2007
まとめ
筋肉の衛星細胞は,幹細胞と祖先細胞の混合体です. ニッチ内の幹細胞の非対称な分裂は,筋肉の修復のためにこれらの独特の細胞集団を生成します.
科学分野:
- 筋肉の生物学について
- 細胞・分子生物学 細胞・分子生物学
- 再生医学は再生医学である.
背景:
- 衛星細胞は,損傷後の筋肉の維持と再生に不可欠です.
- 衛星細胞の異質性を理解することは,その再生の可能性を解き放つための鍵です.
関連する概念動画
Determining the Plane of Cell Division
3.8K
Positioning the cell division plane is a critical step during development and cell differentiation, particularly during mitosis when the plane is essential for determining the size of the two daughter cells. The cell division plane is perpendicular to the plane of chromosome segregation, but different types of organisms have different cell division mechanisms to suit their morphology and function.
Animal cells
In animal cells, the cleavage furrow forms along the plane of cell division...
Animal cells
In animal cells, the cleavage furrow forms along the plane of cell division...
3.8K
Molecular Factors Affecting Cell Division
3.9K
Several external and internal factors influence the initiation and inhibition of cell division. For instance, the death of nearby cells or the release of human growth hormone (hGH) promotes cell division. In contrast, lack of hGH or crowding of cells can inhibit cell division.
Several proteins function as internal regulators to ensure each cell cycle stage is completed faithfully before proceeding to the next. Regulator molecules may act directly or influence the activity or production of other...
Several proteins function as internal regulators to ensure each cell cycle stage is completed faithfully before proceeding to the next. Regulator molecules may act directly or influence the activity or production of other...
3.9K
Satellite Stem Cells and Muscular Dystrophy
2.3K
Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...
2.3K
The Role of Actin and Myosin in Non-muscle Cells
4.7K
Actin and myosin or actomyosin filaments also play a significant role in cells other than those involved in muscle contraction (which occurs within the sarcomere of muscle cells). The mechanism of non-muscle cell contractile bundles was first observed in Dictyostelium and Acanthamoeba. In non-muscle cells, two bundles are commonly found: stress fibers and actomyosin adherence belts. These contractile bundles are smaller and less organized than the ones found in muscle cells. They are held...
4.7K
Energy of a Satellite in a Circular Orbit
3.0K
Thousands of artificial satellites orbit the Earth every day at various distances from the Earth. Satellites that orbit the Earth below an altitude of 1,600 km are considered to be orbiting in low-Earth orbit (LEO). Research satellites and Earth observation satellites are usually placed in LEO, and mostly orbit the Earth in elliptical orbits. Navigation satellites are placed in medium-Earth orbit (MEO), ranging from 2,000 km to 36,000 km from the surface of the Earth. Meanwhile, communication...
3.0K
Functional Divisions of the Nervous System
8.0K
The nervous system, responsible for sensing, integrating, and responding to various stimuli, is divided into the central nervous system (CNS) and the peripheral nervous system (PNS). The PNS has two functional divisions: the sensory or afferent division and the motor or efferent division.
The sensory division transmits information from sensory receptors in the body to the CNS. It provides the CNS with knowledge about somatic senses (such as tactile, thermal, pain, and proprioceptive sensations)...
The sensory division transmits information from sensory receptors in the body to the CNS. It provides the CNS with knowledge about somatic senses (such as tactile, thermal, pain, and proprioceptive sensations)...
8.0K


