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Updated: Jul 14, 2026

Comparing the Affinity of GTPase-binding Proteins using Competition Assays
10:37

Comparing the Affinity of GTPase-binding Proteins using Competition Assays

Published on: October 8, 2015

GEFとGAP:小さなGタンパク質の制御における重要な要素

Johannes L Bos1, Holger Rehmann, Alfred Wittinghofer

  • 1Department of Physiological Chemistry and Centre of Biomedical Genetics, UMC Utrecht Universiteitsweg 100, 3584 CG Utrecht, The Netherlands. j.l.bos@umcutrecht.nl

Cell
|June 2, 2007
PubMed
まとめ

グアニヌクレオチド交換因子 (GEFs) とGTPase活性化タンパク質 (GAPs) は,小さなGタンパク質を調節することにより,細胞シグナル伝達を制御する. これらのタンパク質は,がんなどの疾患の重要な治療標的として浮上しています.

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Affinity Precipitation of Active Rho-GEFs Using a GST-tagged Mutant Rho Protein (GST-RhoA(G17A)) from Epithelial Cell Lysates

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Detection of Small GTPase Prenylation and GTP Binding Using Membrane Fractionation and GTPase-linked Immunosorbent Assay13:51

Detection of Small GTPase Prenylation and GTP Binding Using Membrane Fractionation and GTPase-linked Immunosorbent Assay

Published on: November 11, 2018

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GTPases and their Regulation02:14

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