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Updated: Jul 10, 2026

DamID-seq: Genome-wide Mapping of Protein-DNA Interactions by High Throughput Sequencing of Adenine-methylated DNA Fragments
09:14

DamID-seq: Genome-wide Mapping of Protein-DNA Interactions by High Throughput Sequencing of Adenine-methylated DNA Fragments

Published on: January 27, 2016

in vivoのタンパク質-DNA相互作用の全ゲノムマッピング

David S Johnson1, Ali Mortazavi, Richard M Myers

  • 1Department of Genetics, Stanford University School of Medicine, Stanford, CA, 94305-5120, USA.

Science (New York, N.Y.)
|June 2, 2007
PubMed
まとめ

ChIP-Seqを使ってタンパク質-DNAの相互作用をマッピングし,1946年にニューロン制限サイレンサー因子 (NRSF) の結合部位を特定しました. これは新しい結合モチーフと潜在的な遺伝子標的を明らかにし,遺伝子調節に関する理解を深める.

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