この患者さんは認知症ですか?

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Updated: May 1, 2026

The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease
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The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease

Published on: October 13, 2016

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Tracey Holsinger1, Janie Deveau, Malaz Boustani

  • 1Department of Psychiatry, Durham VA Medical Center, Durham, NC, USA. tracey.holsinger@va.gov

JAMA
|June 7, 2007
PubMed
まとめ

短期的な認知スクリーニングテストは,初等医療における認知症の診断に役立ちます. The Memory Impairment Screenとインフォマントレポートは,高齢者の認知障害を検出する有望なことを示しています.

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Alzheimer disease involves structural changes in the brain that begin long before symptoms appear. The most distinctive features are extracellular neuritic plaques and intracellular neurofibrillary tangles.Neuritic plaques form in the cerebral cortex and around blood vessels. These plaques contain a dense core of beta-amyloid (Aβ)—a toxic protein fragment that clumps outside neurons. The core is surrounded by damaged neuronal extensions, as well as reactive astrocytes and...
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