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Updated: Jul 14, 2026

Evaluation of Substrate Ubiquitylation by E3 Ubiquitin-ligase in Mammalian Cell Lysates
09:47

Evaluation of Substrate Ubiquitylation by E3 Ubiquitin-ligase in Mammalian Cell Lysates

Published on: May 10, 2022

SCFCdc4ダイマーの表面的な指向は,基板のユビキチネーションのための複数の幾何学に対応します

Xiaojing Tang1, Stephen Orlicky, Zhenyuan Lin

  • 1Centre for Systems Biology, Samuel Lunenfeld Research Institute, Toronto, Ontario, Canada M5G 1X5.

Cell
|June 19, 2007
PubMed
まとめ

SCFユビキチンリガゼのDドメインはジマーを形成し,基板のユビキチン化を強化する. この二重化は,基板とユビキチン鎖における多様なライシン幾何学に対応することによって,触媒効率を最適化します.

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