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Updated: Jul 14, 2026

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
07:15

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

一般的なNOS1AP変異は,ロッテルダム研究でQTc間隔の延長と関連しています

Albert-Jan L H J Aarnoudse1, Christopher Newton-Cheh, Paul I W de Bakker

  • 1Department of Epidemiology and Biostatistics, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

Circulation
|June 20, 2007
PubMed
まとめ

NOS1AP遺伝子の一般的な変異は,高齢者のQT間隔の長さに著しく影響を与えます. しかし,この研究では,これらの遺伝的変異と突然心臓死のリスクとの明確な関連性が見つかりませんでした.

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Electrocardiogram Recordings in Anesthetized Mice using Lead II

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