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Updated: Jul 11, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
10:27

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells

Published on: March 9, 2012

核アクチンは,SRFコファクターMALのダイナミックな細胞下局部化と活性を調節する

Maria K Vartiainen1, Sebastian Guettler, Banafshe Larijani

  • 1Transcription Laboratory, Cancer Research UK, London Research Institute, Lincoln's Inn Fields Laboratories, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

Science (New York, N.Y.)
|June 26, 2007
PubMed
まとめ

核アクチンは,血清応答因子 (SRF) のコアクティベーターであるMALを制御することによって,遺伝子発現を調節します. 血清刺激はアクチンポリメリゼーションを誘発し,MAL核輸出を阻害し,転写を活性化します.

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