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Updated: Jul 1, 2026

Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography
09:09

Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography

Published on: September 20, 2016

阻害剤に結合したヒトの5-リポキシゲナーゼ活性化タンパク質の結晶構造

Andrew D Ferguson1, Brian M McKeever, Shihua Xu

  • 1Department of Medicinal Chemistry, Merck Research Laboratories, Rahway, NJ 07065, USA.

Science (New York, N.Y.)
|June 30, 2007
PubMed
まとめ

研究者らは,ルオコトリエン生物合成を阻害する構造的基礎を明らかにした. FLAP阻害体がどのように結合するかを理解することは,炎症性呼吸器系および心血管疾患の治療法を開発するための新しい道を提供します.

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Crystal Structure of the N-terminal Domain of Ryanodine Receptor from Plutella xylostella

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Targeted Antibody Blocking by a Dual-Functional Conjugate of Antigenic Peptide and Fc-III Mimetics (DCAF)09:39

Targeted Antibody Blocking by a Dual-Functional Conjugate of Antigenic Peptide and Fc-III Mimetics (DCAF)

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