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Updated: May 20, 2026

In Vitro Analysis of E3 Ubiquitin Ligase Function
06:06

In Vitro Analysis of E3 Ubiquitin Ligase Function

Published on: May 14, 2021

連続的なE2sは,APCのターゲットに対するポリユビキチンチェーンアセンブリを駆動します

Monica C Rodrigo-Brenni1, David O Morgan

  • 1Department of Physiology, University of California, San Francisco, CA 94158, USA.

Cell
|July 17, 2007
PubMed
まとめ

アナフェーズ促進複合体 (APC) は,ユビキチン鎖の組み立てのために,連続的なE2酵素,Ubc4とUbc1を使用します. このメカニズムは,細胞サイクル進行と標的タンパク質のタンパク質破壊に不可欠です.

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