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Updated: Jul 9, 2026

Crystallizing Membrane Proteins for Structure Determination using Lipidic Mesophases
22:00

Crystallizing Membrane Proteins for Structure Determination using Lipidic Mesophases

Published on: November 21, 2010

ヒトの膜タンパク質の結晶構造は,システニルルクオートリエンの生物合成に関与する

Hideo Ago1, Yoshihide Kanaoka, Daisuke Irikura

  • 1Structural Biophysics Laboratory, RIKEN SPring-8 Center, Harima Institute, 1-1-1 Kouto, Sayo, Hyogo 679-5148, Japan.

Nature
|July 17, 2007
PubMed
まとめ

システニルルクオトリエン合成酵素 (LTC4S) は,ルクオトリエンC4 (LTC4) の生成を触媒化する. ヒトのLTC4Sの原子構造をグルタチオンで決定し,新しい抗炎症薬の開発に不可欠な基板特異性を明らかにしました.

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